Macrocyclic complexes: synthesis and characterization

نویسنده

  • DHARMPAL SINGH
چکیده

A no vel series of co mplexes of the type [M(C28H24N4)X]X2, where M = Cr(III), Fe(III) or Mn(III), X = Cl−, NO3, CH3COO and (C28H24N4) corresponds to the tetradentate macrocyclic ligand, were synthesized in methanolic media by the template condensation of 1,8-diaminonaphthalene and 2,3-butanedione (diacetyl) in the presence of trivalent metal salts. The complexes were characterized by elemental analyses, conductance and magnetic measurements, and U V/Vis an d IR spectroscopy. Based on these studies, a five-coor dinate square pyramidal geometry for all the prepared co mplexes is proposed. All the synthesized macrocyclic co mplexes were test ed for their in vitro anti fungal activity against so me fung al strains viz. Aspergillus niger a nd A. fumigatus. The results obt ained were co mpared with t he stand ard an tifungal drug fluconazole.

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تاریخ انتشار 2010